MKLN1
MKLN1 is a gene catalogued in the canine genome. Below are the inherited conditions OMIA links to it in dogs, its human counterpart, and its canonical records across the genomics world.
The inherited conditions OMIA associates with MKLN1 in dogs. Each links to the full record.
MKLN1 as it is catalogued across the genomics world. Each link is the canonical record, so this gene composes with everything those resources know.
In humans, this gene's counterpart is MKLN1. That ortholog is what connects MKLN1 to a century of human medical genetics. The dog and human proteins are 99% identical.
In people, MKLN1 rarely tolerates loss-of-function variation (gnomAD v4.1 constraint, LOEUF 0.44), a sign it does important, dosage-sensitive work.
Lookup and discovery are candidate-framed research surfaces. Classification renders AVCG grades we cite; Sniff does not score variants with a model of its own.
Per-breed allele frequencies across the atlas are surfaced for the trait loci Sniff has verified a direction-of-effect for. For MKLN1 we show the cited identity and disease associations, and we would rather show you exactly that than a frequency we cannot yet interpret honestly. See the gene catalog for trait loci with frequency views and every disease-linked gene page.
Gene identity and disease associations are grounded in OMIA (CC-BY) and the open Sniff Atlas. Full citation formats at sniff.world/cite.