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snıff

Research instrument · Spectra

Where does independent evidence agree?

Pick a scientific job below. Sniff will show genes where dog and human evidence both ring, how many independent layers agree, where tumor biology diverges honestly, and where our coverage is uneven (not a verdict about importance).

… genes with both a canine signal and human evidence. Every lit layer is a cited count you can open. A flat layer means we have not looked there yet.

What do you want to find?

Start here · a clear finding

ABCA4

Loading the live spectrum for ABCA4…

Require a layer lit (stack filters)

… genes

What this is. A recount of cited evidence, never a score of our own. “Layers that agree” counts independent channels; each traces to its source. We render and cite others' classifications; we do not model variants ourselves.

Study depth is secondary. PubMed gene–PMID counts (NCBI gene2pubmed) label well-studied vs less-studied genes so high agreement is not mistaken for novelty. Sort by “surprisingly dense for PubMed fame” to put high-agreement, lower-citation genes first. Not a quality score.

Gene-level, candidate-not-verdict. A lit human layer means the human gene carries that evidence, never that a dog allele equals a human one. A cross-species match is a candidate model to test.

Dissonance (INV-81). Disagreement only when both sides are cited on a comparable lesion. See also comparative oncology.

Darkness is a result. A flat layer is unexplored or absent in our join, not “nothing in biology.”

Sources: OMIA · Dog10K · ClinVar · gnomAD · Mondo/Monarch · orthology methods · AVCG (Boeykens 2024) · oncology cohorts. Each lit segment cites its own.