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Cancer-driver node · fused signature

DMD

Every register Sniff holds about DMD, in one place, each strand cited to its source. This is a gene-level, model-of view of somatic cohort frequencies and human evidence, never a germline carrier status for an individual dog and never a per-dog prediction.

Somatic driver in canine cancer

The fraction of sequenced tumors somatically altered in DMD, per cancer, from peer-reviewed cohorts. A cohort rate, not an individual-dog risk. Each cancer carries its cross-species concordance: whether the dog and human agree on this driver (commensurability-gated, INV-81).

Translational evidence balance
dog-ahead (unaudited) · +0.333

The dog side carries more cited disease evidence. This is unaudited: it can mean the dog literature is genuinely ahead, or that our human ingestion is incomplete (the HEXA class). It is not a target until that is ruled out. Coverage, not importance. D = 2 dog vs H = 1 human cited disease channels.

Human constraint
not held
Germline (human)
no germline syndrome (a true negative, not a gap)
Dog↔human ortholog
high
3 methods · 94.98% identity