chr18:20,697,946 in FGF4_retrogene_CFA18
Representative variant at the FGF4_retrogene_CFA18 leg length locus on CanFam4 (UU_Cfam_GSD_1.0). Alleles T/C. chondrodysplasia insertion site; not annotated as gene Per-breed allele frequencies are on the FGF4_retrogene_CFA18 gene page. Predicted disease relevance at the per-dog level is UNPROVEN; this variant tags a morphology locus, not a clinical phenotype.
- CanFam4 position
- chr18:20,697,946
- Alleles
- T / C
- Linked gene
- FGF4_retrogene_CFA18
- Trait association
- leg length
- Reference assembly
- CanFam4 (UU_Cfam_GSD_1.0)
- Source dataset
- Sniff Atlas v1.0.1
Per-breed frequencies + pathogenicity
Per-breed allele frequencies at this position render on the FGF4_retrogene_CFA18 gene page. For programmatic access, query the Sniff MCP at mcp.sniff.world or run bcftools directly against the Atlas sites VCF:
tabix sniff_atlas.sites.vcf.gz 18:20697946Returns global AF, popmax breed, ESM2 LLR, Pangolin splice score, phyloP 241-way conservation, and the low-DR2 flag in the INFO column. Header carries source, version, license, and DOI. Download from the Zenodo record.
Citations
Cite the Sniff Atlas DOI for the breed-stratified frequencies and the upstream CanVAS preprint for the genotype substrate:
Gehring, M. (2026). Sniff Atlas v1.0.1. Zenodo. https://doi.org/10.5281/zenodo.20566358. CC-BY 4.0.
Brundage, D. M., et al. (2026). CanVAS: A Harmonized and Imputed Canine Variant Atlas. bioRxiv. https://doi.org/10.64898/2026.04.13.718238.
Full citation formats at sniff.world/cite.
Related
- FGF4_retrogene_CFA18 gene page — per-breed allele frequencies at this representative SNP, biological notes, direction of effect.
- Sniff Atlas v1.0.1 — the source dataset.
- All variants in the trait-loci index