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CanVAS JenkinsWGS · Founder
Cosmic medallion portrait of ES_32888_ES_32888, a English Setter
AI portrait
About this portrait

This portrait was algorithmically built from this dog's genome: their genotype at 8 morphology loci (coat length, curl, color, ear set, body size, head shape, skull, furnishings) plus their position within the 14,478-dog atlas. The same dog always reproduces the same portrait. A different dog with different alleles gets a different portrait.

ES_32888_ES_32888

ES_32888_ES_32888 is a English Setter from the JenkinsWGS research cohort. One of 14,478 dogs who built the atlas.

See ES_32888_ES_32888 in the atlas
About ES_32888_ES_32888

ES_32888_ES_32888 is a notable English Setter - distinctive within the breed.

  • Predicted giant by the six body-size genes the atlas reads (IGF1, HMGA2, SMAD2, LCORL, STC2, ADAMTS17).
  • Standard leg length. No chondrodysplasia retrogene variant.
  • Smooth coat. No wire-furnishings variant at RSPO2.
ES_32888_ES_32888's nearest neighbors

The five dogs in the atlas whose genomes sit closest to ES_32888_ES_32888's. Click any of them to keep exploring.

  1. 14166_14166 English Setter 25.10
  2. 14167_14167 English Setter 25.42
  3. 19448_19448 English Setter 25.74
  4. 15863_15863 English Setter 25.93
  5. 19447_19447 English Setter 25.94
ES_32888_ES_32888's breed

ES_32888_ES_32888 sits in the English Setter cluster, with genome overlap to Labrador Retriever, and Golden Retriever - sister breeds nearby in the atlas.

Breed similarity from non-negative least squares against 91 breed centroids in PCA-256 space, corrected for atlas sample-size imbalance. Without correction, Goldens (22% of the atlas) leak into every dog's raw NNLS breakdown; with it, the bias falls out. Raw fractions stay in the dataset for re-derivation. Methodology.

  1. English Setter 84%
  2. Labrador Retriever 9%
  3. Golden Retriever 7%
Source

From the CanVAS (JenkinsWGS cohort) . Breed-page reference: English Setter.

Full genotype detail
click to expand

The actual allele call at each locus's representative SNP for this dog. Each gene name links to its page where you can see the per-breed frequency table and the direction of effect.

Body size
IGF1 C/C
HMGA2 T/T
SMAD2 A/A
LCORL G/G
STC2 C/A
ADAMTS17 A/A
Leg length
FGF4·CFA18 C/C
FGF4·CFA12 C/C
Coat
RSPO2 C/C
FGF5 C/C
KRT71 C/C
MC1R C/C
Ear set
MSRB3 A/A
Skull shape
BMP3 T/T
SMOC2 G/G
Technical details
click to expand

The numbers behind the placement. Useful for researchers reproducing the math or debugging an unexpected position; not interesting to most readers.

UMAP-3D position
x 1.010
y 6.477
z 15.755
PCA-256 distance from breed centroid
57.97
Outlier percentile in breed
86
lower = more typical
Top-3 principal components by |z|

The 3 PCs on which ES_32888_ES_32888 scores most extreme, with the 3 highest-loading SNPs on each. Foundation for the future genome-ring visualization.

PC75 z = -11.24
  • chr24:13,342,362 loading 0.0352
  • chr3:60,753,270 loading -0.0318
  • chr6:19,557,398 loading 0.0285
PC76 z = -9.90
  • chr3:2,052,050 loading 0.0310
  • chr17:4,233,511 loading 0.0298
  • chr3:2,363,106 loading 0.0297
PC9 z = -7.54
  • chr3:66,503,138 loading 0.0243
  • chr29:24,433,584 loading 0.0237
  • chr21:33,291,005 loading 0.0234
Ancestry reconstruction error: 0.60