MC1R
recessive red e/e; Ensembl symbol fails; chr5 region
MC1R chr5. The e/e locus: recessive yellow/red coat. Direction calibrated against e/e breeds (Golden, Irish Setter, NSDTR) vs pigmented controls.
allele common in pigmented/E-locus dominant-black-capable breeds
allele common in recessive-red (e/e) breeds (Golden, Irish Setter, NSDTR)
Where the coat color variant sits across every breed with data, by allele frequencyAllele frequencyWhat it isHow common a gene variant is across dogs, from 0% (none carry it) to 100% (all do).For your dogA high number means it's common in the breed. It does not tell you whether your own dog carries it.PreciselyThe proportion of sampled chromosomes in a population that carry the variant allele.Sniff Atlas (CanVAS) · measured · Ask about this → and grouped by AKC breed groupAKC breed groupWhat it isThe American Kennel Club's grouping of breeds by the job they were bred for: Sporting, Hound, Working, Herding, Terrier, Toy, Non-Sporting.PreciselyAKC parent-group classification. A registry convention reflecting historical use, not a genetic grouping.American Kennel Club · registry convention. Each tick is one breed; a variant fixed in one group and absent in another shows up as a gap. These come from one marker per trait, so read them as a tag, not a verdictA trait tag, not a verdictWhat it isThese frequencies come from one marker per trait. It predicts the trait for most breeds, but there are real exceptions.For your dogRead it as a tendency for the breed, never as a guarantee about your dog. One marker is not the whole story.PreciselySingle-SNP trait proxies are population tags, not deterministic genotype-to-phenotype calls. Penetrance, modifier loci, and breed-specific haplotypes cause exceptions (for example, the MSRB3 ear-type tag misreads Toy Poodles and Belgian Sheepdogs).Sniff Atlas methodology · known limitation, stated · Ask about this →: accurate for most breeds, with real exceptions.
- 100% n=100
- 100% n=37
- 100% n=32
- 100% n=30
- 100% n=30
- 100% n=26
- 100% n=25
- 100% n=25
- 100% n=20
- 100% n=532
- 3% n=32
- 16% n=52
- 21% n=31
- 29% n=102
- 31% n=286
- 32% n=118
- 35% n=24
- 37% n=67
- 39% n=3523
- 42% n=117
105 breeds with fewer than 20 genotyped dogs are not ranked here. At that sample size a single dog swings the frequency, so the figure is not yet stable enough to compare.
Frequency is measured at the typed-backbone 5:63544121 on chr5, 63.5 Mb (44 kb from the gene body). Alleles T/C. Coordinates from manual position (Ensembl symbol failed). Per-breed frequencies are computed across all CanVAS dogs labelled with that breed (missing genotypes excluded).
MC1R as it is catalogued across the genomics world. Each link is the canonical record, so this gene composes with everything those resources know.
In humans, this gene's counterpart is MC1R. That ortholog is what connects MC1R to a century of human medical genetics.
The per-breed allele frequencies on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). The underlying genotype substrate is CanVAS (Brundage 2026, doi:10.64898/2026.04.13.718238), and disease associations are grounded in OMIA. Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.