Skip to main content
snıff
Body Size

SMAD2

chr7:43,688,668-43,762,252 · UU_Cfam_GSD_1.0

small vs giant strong differentiation chr7

Atlas-wide
Frequency
74%
dog-weighted average
Breeds with data
208
of 215
Dogs contributing
13,523
CanVAS Atlas
What the frequency means

SMAD2 chr7:43.7Mb. Strong size-discriminating locus identified by Plassais 2019. Direction: SMALL vs GIANT (note: opposite sign convention from IGF1/HMGA2 at this rep SNP).

High frequency means

allele common in giant breeds

Low frequency means

allele common in small breeds

Top 10 breeds, highest frequency
  1. Collie herding
    100% n=20
  2. Curly Coated Retriever sporting
    100% n=8
  3. Finnish Spitz non_sporting
    100% n=22
  4. Great Pyrenees working
    100% n=20
  5. Guangxi Hound hound
    100% n=12
  6. Irish Water Spaniel sporting
    100% n=12
  7. Liangzhou Dog other
    100% n=12
  8. Newfoundland working
    100% n=182
  9. Rhodesian Ridgeback working
    100% n=19
  10. Shetland Sheepdog herding
    100% n=37
Bottom 10 breeds, lowest frequency
  1. Toy Fox Terrier toy
    0% n=8
  2. Tibetan Terrier non_sporting
    0% n=9
  3. Silky Terrier toy
    0% n=9
  4. Shih Tzu toy
    0% n=38
  5. Pug toy
    0% n=31
  6. Japanese Chin toy
    0% n=8
  7. Yorkshire Terrier toy
    2% n=228
  8. Bichon Frise toy
    3% n=32
  9. Pekingese toy
    4% n=26
  10. Chihuahua toy
    6% n=25
Methodology

Frequency is measured at the typed-backbone 7:43693994 on chr7, 43.7 Mb (inside the gene body). Alleles A/G. Coordinates from ensembl symbol UU Cfam GSD 1.0. Per-breed frequencies are computed across all CanVAS dogs labelled with that breed (missing genotypes excluded). See methodology for the full pipeline.

Last updated
Sources: CanVAS (Brundage 2026) · OMIA · Dog10K (Meadows 2023)