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CanVAS Spatola · Founder
Cosmic medallion portrait of ISET_ISET_15E12, a Irish Setter
AI portrait
About this portrait

This portrait was algorithmically built from this dog's genome: their genotype at 8 morphology loci (coat length, curl, color, ear set, body size, head shape, skull, furnishings) plus their position within the 14,478-dog atlas. The same dog always reproduces the same portrait. A different dog with different alleles gets a different portrait.

ISET_ISET_15E12

ISET_ISET_15E12 is a Irish Setter from the Spatola research cohort. One of 14,478 dogs who built the atlas.

See ISET_ISET_15E12 in the atlas
About ISET_ISET_15E12

ISET_ISET_15E12 is a notable Irish Setter - distinctive within the breed.

  • Predicted large by the six body-size genes the atlas reads (IGF1, HMGA2, SMAD2, LCORL, STC2, ADAMTS17).
  • Standard leg length. No chondrodysplasia retrogene variant.
  • Carrier of the RSPO2 wire-coat variant (single copy).
ISET_ISET_15E12's nearest neighbors

The five dogs in the atlas whose genomes sit closest to ISET_ISET_15E12's. Click any of them to keep exploring.

  1. ISET_ISET_13H10 Irish Setter 13.94
  2. ISET_ISET_15B10 Irish Setter 14.46
  3. ISET_ISET_15A12 Irish Setter 14.55
  4. ISET_ISET_13A10 Irish Setter 15.39
  5. ISET_ISET_15F10 Irish Setter 15.63
ISET_ISET_15E12's breed

ISET_ISET_15E12 sits in the Irish Setter cluster, with genome overlap to Labrador Retriever, and Golden Retriever - sister breeds nearby in the atlas.

Breed similarity from non-negative least squares against 91 breed centroids in PCA-256 space, corrected for atlas sample-size imbalance. Without correction, Goldens (22% of the atlas) leak into every dog's raw NNLS breakdown; with it, the bias falls out. Raw fractions stay in the dataset for re-derivation. Methodology.

  1. Irish Setter 71%
  2. Labrador Retriever 17%
  3. Golden Retriever 12%
Source

From the CanVAS (Spatola cohort) . Breed-page reference: Irish Setter.

Full genotype detail
click to expand

The actual allele call at each locus's representative SNP for this dog. Each gene name links to its page where you can see the per-breed frequency table and the direction of effect.

Body size
IGF1 A/A
HMGA2 T/T
SMAD2 A/A
LCORL G/G
STC2 C/C
ADAMTS17 G/A
Leg length
FGF4·CFA18 C/C
FGF4·CFA12 C/C
Coat
RSPO2 C/T
FGF5 C/C
KRT71 T/C
MC1R T/C
Ear set
MSRB3 G/G
Skull shape
BMP3 C/C
SMOC2 A/A
Technical details
click to expand

The numbers behind the placement. Useful for researchers reproducing the math or debugging an unexpected position; not interesting to most readers.

UMAP-3D position
x -3.212
y 5.398
z 3.907
PCA-256 distance from breed centroid
60.65
Outlier percentile in breed
87
lower = more typical
Top-3 principal components by |z|

The 3 PCs on which ISET_ISET_15E12 scores most extreme, with the 3 highest-loading SNPs on each. Foundation for the future genome-ring visualization.

PC205 z = 5.59
  • chr28:15,673,727 loading 0.0386
  • chr7:26,386,959 loading -0.0358
  • chr7:26,293,949 loading -0.0338
PC112 z = 5.05
  • chr3:6,565,383 loading 0.0418
  • chr18:10,714,022 loading 0.0387
  • chr3:6,720,531 loading 0.0365
PC252 z = -4.67
  • chr19:30,132,204 loading 0.0320
  • chr25:21,796,415 loading -0.0316
  • chr3:5,565,848 loading 0.0303
Ancestry reconstruction error: 0.40
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