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CanVAS Hayward2016 · Founder
Cosmic medallion portrait of PFZ22A10_PFZ22A10, a English Setter
AI portrait
About this portrait

This portrait was algorithmically built from this dog's genome: their genotype at 8 morphology loci (coat length, curl, color, ear set, body size, head shape, skull, furnishings) plus their position within the 14,478-dog atlas. The same dog always reproduces the same portrait. A different dog with different alleles gets a different portrait.

PFZ22A10_PFZ22A10

PFZ22A10_PFZ22A10 is a English Setter from the Hayward2016 research cohort. One of 14,478 dogs who built the atlas.

See PFZ22A10_PFZ22A10 in the atlas
About PFZ22A10_PFZ22A10

PFZ22A10_PFZ22A10 sits near the center of the English Setter cluster - genetically very typical for the breed.

  • Predicted large by the six body-size genes the atlas reads (IGF1, HMGA2, SMAD2, LCORL, STC2, ADAMTS17).
  • Carries one copy of the FGF4 chondrodysplasia retrogene.
  • Smooth coat. No wire-furnishings variant at RSPO2.
PFZ22A10_PFZ22A10's nearest neighbors

The five dogs in the atlas whose genomes sit closest to PFZ22A10_PFZ22A10's. Click any of them to keep exploring.

  1. PFZ20F10_PFZ20F10 English Setter 13.55
  2. PFZ21F02_PFZ21F02 English Setter 14.50
  3. PFZ22E12_PFZ22E12 English Setter 14.95
  4. PFZ21H04_PFZ21H04 English Setter 15.04
  5. PFZ22F09_PFZ22F09 English Setter 15.21
PFZ22A10_PFZ22A10's breed

PFZ22A10_PFZ22A10 sits in the English Setter cluster, with genome overlap to Labrador Retriever - sister breeds nearby in the atlas.

Breed similarity from non-negative least squares against 91 breed centroids in PCA-256 space, corrected for atlas sample-size imbalance. Without correction, Goldens (22% of the atlas) leak into every dog's raw NNLS breakdown; with it, the bias falls out. Raw fractions stay in the dataset for re-derivation. Methodology.

  1. English Setter 94%
  2. Labrador Retriever 6%
Source

From the CanVAS (Hayward2016 cohort) . Breed-page reference: English Setter.

Full genotype detail
click to expand

The actual allele call at each locus's representative SNP for this dog. Each gene name links to its page where you can see the per-breed frequency table and the direction of effect.

Body size
IGF1 C/C
HMGA2 T/T
SMAD2 A/G
LCORL G/G
STC2 A/A
ADAMTS17 G/A
Leg length
FGF4·CFA18 T/C
FGF4·CFA12 C/C
Coat
RSPO2 C/C
FGF5 C/C
KRT71 C/C
MC1R C/C
Ear set
MSRB3 A/A
Skull shape
BMP3 T/T
SMOC2 G/G
Technical details
click to expand

The numbers behind the placement. Useful for researchers reproducing the math or debugging an unexpected position; not interesting to most readers.

UMAP-3D position
x 0.725
y -2.150
z -3.442
PCA-256 distance from breed centroid
18.44
Outlier percentile in breed
2
lower = more typical
Top-3 principal components by |z|

The 3 PCs on which PFZ22A10_PFZ22A10 scores most extreme, with the 3 highest-loading SNPs on each. Foundation for the future genome-ring visualization.

PC9 z = -8.15
  • chr3:66,503,138 loading 0.0243
  • chr29:24,433,584 loading 0.0237
  • chr21:33,291,005 loading 0.0234
PC7 z = 2.56
  • chr17:45,883,815 loading 0.0290
  • chr17:6,654,333 loading 0.0283
  • chr34:27,183,296 loading 0.0282
PC11 z = 2.25
  • chr6:60,987,558 loading 0.0302
  • chr18:25,790,852 loading 0.0293
  • chr14:14,074,192 loading -0.0293
Ancestry reconstruction error: 0.19
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