CanVAS Spatola · Founder

STAF_STAF_27382

STAF_STAF_27382 is a Staffordshire Bull Terrier from the Spatola research cohort. One of 14,478 dogs who built the atlas.

See STAF_STAF_27382 in the atlas

About this name and portrait

I'm sure you probably guessed by now. These aren't real pictures of these dogs. And these aren't their real names.

But these dogs were real. They were alive. They were loved. We thought they deserved more than a subject ID to be remembered by. The portraits are built from each dog's actual genome, so we tried to get it close. But it's not enough.

We want to see your dog's face. We want to celebrate them by the name they were loved by. We want to look back and say 'oh yeah, Bosco? The Dachshund-Corgi mix? I remember him, his FGF4 variant was wild, those little legs could hold a small house.'

These dogs gave something most people don't realize. The Heroes in the Golden Retriever Lifetime Study showed up for blood draws, health surveys, fur and nail samples, every single year. Some of them for 14 years. Their data has taught us about lymphoma, hemangiosarcoma, and aging in ways that help not just dogs but potentially humans. And they didn't ask for any of it.

Morris Animal Foundation calls them Heroes. We agree.

If your dog was part of any of these studies, we want to give you their page. Their real name. Their real photo. The recognition they earned.

Email [email protected].

About STAF_STAF_27382

STAF_STAF_27382 is a strong genetic outlier within the Staffordshire Bull Terrier cluster - among the most distinctive examples of their breed.

Predicted large by the six body-size genes the atlas reads (IGF1, HMGA2, SMAD2, LCORL, STC2, ADAMTS17).
Carries one copy of the FGF4 chondrodysplasia retrogene.
Carrier of the RSPO2 wire-coat variant (single copy).

STAF_STAF_27382's nearest neighbors

The five dogs in the atlas whose genomes sit closest to STAF_STAF_27382's. Click any of them to keep exploring.

STAF_STAF_27382's breed

STAF_STAF_27382 sits in the Staffordshire Bull Terrier cluster, with genome overlap to Labrador Retriever, and Golden Retriever - sister breeds nearby in the atlas.

Breed similarity from non-negative least squares against 91 breed centroids in PCA-256 space, corrected for atlas sample-size imbalance. Without correction, Goldens (22% of the atlas) leak into every dog's raw NNLS breakdown; with it, the bias falls out. Raw fractions stay in the dataset for re-derivation. Methodology.

Source

From the CanVAS (Spatola cohort) . Breed-page reference: Staffordshire Bull Terrier.

Full genotype detail

click to expand

The actual allele call at each locus's representative SNP for this dog. Each gene name links to its page where you can see the per-breed frequency table and the direction of effect.

Body size

IGF1	–
HMGA2	T/T
SMAD2	A/G
LCORL	G/G
STC2	C/A
ADAMTS17	–

Leg length

FGF4·CFA18	C/C
FGF4·CFA12	T/C

Coat

RSPO2	C/T
FGF5	T/T
KRT71	C/C
MC1R	T/T

Ear set

MSRB3

–

Skull shape

BMP3	–
SMOC2	A/G

Technical details

click to expand

The numbers behind the placement. Useful for researchers reproducing the math or debugging an unexpected position; not interesting to most readers.

UMAP-3D position

x 0.707
y 0.649
z 2.688

PCA-256 distance from breed centroid

27.44

Outlier percentile in breed

100

lower = more typical

Top-3 principal components by |z|

The 3 PCs on which STAF_STAF_27382 scores most extreme, with the 3 highest-loading SNPs on each. Foundation for the future genome-ring visualization.

PC196 z = 2.82

chr23:3,426,742 loading 0.0355
chr23:3,756,166 loading 0.0335
chr4:38,305,840 loading 0.0333

PC96 z = -2.69

chr4:32,151,890 loading 0.0295
chr1:72,831,562 loading 0.0294
chr30:30,843,842 loading 0.0291

PC89 z = -2.38

chr25:3,927,722 loading 0.0316
chr25:4,215,319 loading -0.0302
chr25:4,111,134 loading -0.0294

Ancestry reconstruction error: 0.40

Back to the Atlas →