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Bloodhound

Lifespan
9.3 years
95% CI 8.6 to 11 · McMillan 2024, n=134
Most carried variant
Degenerative Myelopathy
23% of 280 tested · Donner 2023
Behind this page
18 dogs
in the atlas · an early sketch · 280 tested for variants

Bloodhounds have a cited life expectancy of 9.3 years (McMillan 2024 / VetCompass, n=134, 95% CI 8.6 to 11). The most carried tested variant is Degenerative Myelopathy, in 23% of 280 Bloodhounds tested (Donner 2023), then Cone-Rod Dystrophy (22%). Only 18 dogs stand behind the atlas figures here, so little is known yet.

Bloodhound
Photo: User:Erland22 · CC BY-SA 4.0 · Wikimedia

Also known as Chien De Saint Hubert, St. Hubert Hound, and Standard Bloodhound.

Mendelian-disease genetics

What genetic diseases do Bloodhounds carry?

From a panel of 250 Mendelian-disease variants screened in 1,054,293 dogs (Donner et al. 2023), Bloodhounds carry 7 of them at observable frequency. Carrier frequency is not clinical risk. Most recessive variants require two copies for disease expression; many dominant variants show incomplete penetrance. Read this as a population fingerprint of what's in the gene pool, not a per-dog prediction.

Degenerative Myelopathy (DM)
Autosomal recessive (Incomplete penetrance)
high 22.5%
n = 280 dogs · 1 variant tested · OMIA:000263-9615 · omia.org →
SOD1what this gene does

SOD1 is a gene that helps protect cells from damage caused by harmful molecules called free radicals.

For your dog: If your dog is a carrier of SOD1 variants, it's worth discussing with your vet, but remember carrier status doesn't mean your dog will get the disease.

Cone-Rod Dystrophy (cord1-PRA/crd4)
Autosomal recessive (Incomplete penetrance)
high 21.8%
n = 280 dogs · 1 variant tested · OMIA:001432-9615 · omia.org →
RPGRIP1what this gene does

RPGRIP1 is a gene involved in the function of photoreceptor cells in the eye, which help dogs see in different light conditions.

For your dog: If your dog belongs to a breed known to carry RPGRIP1 mutations, it’s worth discussing with your vet to understand the risks and monitor eye health.

marker disputed 1.3%
n = 280 dogs · 2 variants tested · OMIA:000162-9615 · omia.org →
PDK4what this gene does

PDK4 helps regulate how cells use energy, especially in the heart muscle.

For your dog: If your dog is one of the breeds known to carry this gene, it’s worth discussing heart health with your vet, but being a carrier doesn’t mean your dog will develop disease.

Shar-Pei Autoinflammatory Disease (SPAID)
Autosomal dominant (Incomplete penetrance)
low 0.54%
n = 280 dogs · 1 variant tested · OMIA:001561-9615 · omia.org →
MTBPwhat this gene does

MTBP is a gene involved in regulating inflammation in the body. It helps control how the immune system responds to triggers.

For your dog: If your dog is from a breed known to carry MTBP variants, it's worth discussing with your vet whether genetic testing or monitoring for inflammation-related issues makes sense.

n = 279 dogs · 1 variant tested · OMIA:000157-9615 · omia.org →
FGF4what this gene does

FGF4 influences leg length by affecting bone growth, leading to shorter legs in certain breeds.

For your dog: If your dog is from a breed known to carry this gene, it's worth discussing spinal health with your vet, but being a carrier doesn’t guarantee problems.

n = 280 dogs · 1 variant tested · OMIA:002539-9615 · omia.org →
n = 280 dogs · 1 variant tested · OMIA:001444-9615 · omia.org →
BEST1what this gene does

BEST1 is a gene that helps maintain the health of the retina, the light-sensitive layer at the back of the eye. It plays a role in keeping the cells in the retina functioning properly.

For your dog: If your dog is from a breed known to carry BEST1 variants, it’s worth discussing retinal health with your vet, especially if you notice any vision changes.

Source: Donner J et al. 2023. Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogs. PLOS Genetics 19(2):e1010651 · Evidence: Limited (DTC ascertainment, tag-SNP proxy) · Confounding MEDIUM · License CC-BY-4.0 · Phene IDs from OMIA (Sydney School of Veterinary Science, The University of Sydney; DOI 10.25910/2AMR-PV70).
Sample size in this breed: 280 dogs from the Donner 2023 cohort.
In plain terms

What these results mean for a Bloodhound

22.5% of Bloodhounds in the Donner 2023 cohort carried it (n=280).

  • DM is a loss of function in the spinal cord that begins in adulthood and progresses to paralysis of the back legs. There is no treatment that stops it.
    OMIA 000263-9615

    “This is an adult onset degeneration of the spinal cord that progresses to paraplegia and tetraparesis. There is no successful treatment. A genetic test is available.” OMIA 000263-9615

  • Two copies of the SOD1 variant mean at risk, not affected. Some dogs with two copies never show signs.
    OMIA 000263-9615

    “some homozygous mutant dogs had no signs of degenerative myelopathy, which suggests incomplete penetrance or other causative loci” OMIA 000263-9615

  • One copy makes a dog a carrier. In the study that found the variant, every affected dog tested had two copies.
    OMIA 000263-9615

    “All affected dogs tested were homozygous mutant.” OMIA 000263-9615

What to do
A DNA result is not a diagnosis. Take the result, and any change in how the dog walks, to a veterinarian.

No test, or a mix
Without a test nobody can say how many copies a dog has. A breed's carrier frequency describes the breed, not this dog.

1.3% of Bloodhounds in the Donner 2023 cohort carried it (n=280).

  • This is a marker, not an established cause. The curated record says a test based on it is not a good indicator of heart disease risk even in Dobermans, the breed it was found in.
    OMIA 000162-9615

    “it is evident that any DNA test based on this marker will not be a good indicator of liability to this disorder in Dobermans” OMIA 000162-9615

What to do
A carrier result for this marker is not, on its own, a reason for heart screening. Heart screening is a conversation with your veterinarian about the breed and the dog.

No test, or a mix
What this marker means in breeds other than the Doberman is not established in the sources this page draws on.

Which Mendelian variants matter most for Bloodhounds?

The Mendelian-disease table above lists seven variants screened in 280 Bloodhounds (Donner 2023). Two matter most by carrier frequency and impact on daily life.

Cone-Rod Dystrophy (cord1-PRA/crd4)

Cone-rod dystrophy in Bloodhounds is a progressive retinal degeneration caused by a recessive variant in RPGRIP1. Affected dogs lose cone-mediated (bright-light) vision first, then rod-mediated (dim-light) vision as the disease advances. The disease typically emerges in middle age. 21.8% of Bloodhounds in the Donner cohort carry one copy (n=280).

Like degenerative myelopathy, the inheritance carries incomplete penetrance. Testing is available. Annual ophthalmologic screening (OFA CAER exam, formerly CERF) is recommended for breeding stock and for any dog with a known carrier status.

What should I feed a Bloodhound?

Bloodhounds were bred for eight-hour hunting days and their metabolism still expects them. Food-motivated weight gain is the most common Bloodhound health failure, and the food bowl is where it starts.

Weight management is the single most consequential feeding decision for this breed. Bloodhounds are scent-driven, food-motivated, and built lean for endurance work. A pet Bloodhound eating maintenance calories while spending most days in a suburban yard will gain weight steadily. Excess body condition accelerates joint wear, complicates cardiac function, and shortens lifespan. The breed’s median lifespan in the sniff.world atlas is 9.3 years (McMillan 2024 / VetCompass) (sniff.world atlas, n=18); owners who keep their dogs lean into their senior years extend that window meaningfully.

Feed measured portions, not ad libitum. A Bloodhound’s appetite does not self-limit. Use a kitchen scale to portion each meal to the target caloric density recommended by the food manufacturer for the dog’s weight and activity level. Most Bloodhounds in pet homes require 15 to 25 percent fewer calories than a kibble’s “active” recommendation suggests. Work with your veterinarian to establish a target weight based on body condition score, not breed standard weight.

Joint health and the growth phase matter, but Bloodhounds are not giant-breed giants. Adult Bloodhounds weigh 80 to 110 pounds. A puppy-stage formulation with controlled calcium (no more than 1.8% dry-matter calcium, per NRC 2006) and a calcium-to-phosphorus ratio between 1.1:1 and 2:1 is appropriate during growth. After 12 months, transition to a maintenance formula with moderate protein (18 to 22 percent) and fat (12 to 15 percent). The breed’s 22.5% carrier frequency for degenerative myelopathy (Donner 2023, n=280) means spinal health is a long-term concern; moderate, consistent weight and adequate but not excessive protein support that.

What we don’t know

The penetrance of degenerative myelopathy and cone-rod dystrophy in Bloodhounds specifically is not yet well characterized. Both variants carry incomplete penetrance in the Donner dataset, but we do not yet know what proportion of Bloodhounds with two disease-associated copies will become symptomatic or at what age. The breed’s small atlas size (18 dogs) limits our ability to track long-term outcomes in genotyped individuals.

Bloodhound lifespan data in the literature is sparse and conflicting. The atlas median of 9.3 years (McMillan 2024 / VetCompass) (sniff.world atlas, n=18) is shorter than some breed-club estimates. This gap may reflect a cohort that skews toward dogs with early health crises, or it may reflect the tendency of owner-reported estimates to exceed verified lifespans. The honest summary is that the gap remains unresolved until more genotyped Bloodhounds are followed longitudinally.

Frequently asked questions about Bloodhounds

Are Bloodhounds good with kids? Yes. Bloodhounds are gentle, pack-oriented dogs with low aggression drive. They were selectively bred for 1,000 years to work cooperatively in large hunts. They are patient with children but will knock over toddlers with their size and enthusiasm; supervision is necessary as with any large dog.

How long do Bloodhounds live? Cited life expectancy is 9.3 years (McMillan 2024 / VetCompass, n=134, 95% CI 8.6 to 11).world atlas, n=18), though some breed-club estimates are higher. Weight management and early screening for degenerative myelopathy and vision loss are the clearest levers owners control to extend lifespan.

What is the most common health problem in Bloodhounds? Obesity is the most common preventable health problem. Degenerative myelopathy (carrier frequency 22.5%, Donner 2023, n=280) and cone-rod dystrophy (carrier frequency 21.8%, Donner 2023, n=280) are the most common genetic risks.

Should I do a DNA test on my Bloodhound? For breeding stock, yes. For a pet Bloodhound, testing for degenerative myelopathy and cone-rod dystrophy will inform screening intervals; dogs with two disease-associated copies benefit from early ophthalmologic exams and neurologic monitoring in middle age.

What causes ear infections in Bloodhounds? Bloodhounds’ long, pendulous ears trap moisture and restrict airflow, creating an ideal environment for bacterial and yeast overgrowth. Weekly ear cleaning with a vet-approved cleanser and prompt drying after swimming or baths are preventive. Otitis externa is common and can become chronic; topical treatment is usually effective.

Are Bloodhounds prone to bloat? Bloat (gastric dilatation-volvulus) is a surgical emergency in large, deep-chested dogs. Bloodhounds are at elevated risk. Feeding multiple small meals rather than one large meal, avoiding exercise immediately after feeding, and knowing the signs of bloat (restlessness, abdominal distension, unsuccessful vomiting attempts) are essential. Consider discussing prophylactic gastropexy with your veterinarian.

Do Bloodhounds shed a lot? Yes. Bloodhounds shed year-round, heavily twice annually. Brush 3 to 4 times weekly to manage loose hair and reduce what ends up on furniture and clothing.

What is the best diet for a Bloodhound? A measured-portion, grain-inclusive, moderate-protein kibble or whole-food diet matched to the individual dog’s activity level and weight. Bloodhounds thrive on consistency and portion control; the best diet is the one the owner can sustain and that keeps the dog lean. Annual body-condition scoring with your veterinarian is more important than the brand name on the bag.

Names & origins

Other names

The Bloodhound is also recorded as Chien De Saint Hubert, St. Hubert Hound, and Standard Bloodhound.

Identified as Bloodhound (VBO:0200175) in the Vertebrate Breed Ontology (Mullen et al. 2025, CC-BY 4.0) · registry IDs FCI 84 · iDog 39 · VeNom 13721.

For researchers Population genetics, disease models and every recorded condition Open the research detail for the Bloodhound
What the atlas says about Bloodhound

In the atlas, the Bloodhound clusters consistently as Bloodhound (100% of the 18 dogs here). Dogs here sit in a relatively sparse region of the atlas, fewer close neighbors than typical.

Low breed predictability score (0.28), individual dogs of this breed vary widely in genetics, suggesting active substructure or sub-population diversity. Only 18 dogs of this breed in the atlas, modestly sampled.

Genetic dimensions · CanVAS atlas

What the atlas genotypes say about Bloodhound

Computed from the 14,478 CanVAS dogs in the Atlas, on an imputed genotype backbone: 77,215 directly typed sites per dog, imputed to 9.67 million variants.

The confidence below counts dogs, not reads: it is the size of the sample, and it is separate from how the genotypes were measured.

These figures are computed from only 18 Bloodhounds in the atlas. Treat them as provisional. They sharpen as more dogs are added.
Dogs in the Atlas
18Founders
10 from Spatola, 7 from Hayward2016, 1 from JenkinsWGS
Genetic diversity

Not enough dogs in the atlas yet (n=18) for a reliable diversity figure. It fills in as more are added.

Mean heterozygosity across the breed. Too few dogs in this breed (<20) to rank.
What does genetic diversity mean?

How varied a breed's gene pool is — the share of gene spots where a typical dog of the breed carries two different versions rather than two identical ones.

How to read it: Higher = more diverse. Among well-sampled breeds it ranges roughly 0.22 (least diverse) to 0.33 (most diverse).

Diversity is a strength, not a verdict on any individual dog. Lower diversity means it's worth paying attention to recessive-risk testing — not that a dog is doomed.

Cluster structure

Not enough dogs in the atlas yet (n=18) to resolve cluster structure. It fills in as more are added.

What does within-breed variation mean?

How much individual dogs within the breed differ from each other genetically.

How to read it: Higher = more internal variety among individuals of the breed.

Sensitive to how many dogs of the breed we've sampled.

Related breeds
Gave rise to
In the Hound group
Explore the full lineage map →
VBO foundation stock (breeding records) · AKC breed group
Relatedness is documented lineage + kennel family. Genetic-ancestry distance measures diversity, not kinship, so it isn't used here.
How long they live
9.3years (life expectancy)
95% CI 8.6–11 · VetCompass, McMillan 2024, n=134. source
What does typical lifespan mean?

The median age dogs of the breed tend to reach.

How to read it: Higher = longer-lived. Compare to longevity-for-size to see whether it's just a size effect.

Drawn from population lifespan records; individual dogs vary widely with care, genetics, and luck.

n = 18 dogs · low sample · CanVAS (Brundage 2026) · Sniff Atlas
A gift to human medicine

Bloodhounds are a natural model for human disease

Because the same genes cause the same conditions across species, the inherited conditions documented in Bloodhounds help researchers understand, and work toward treating, the human diseases they model. This is the dog advancing human medicine. The breed models the human disease; it does not have it, and this is not a prediction for your dog.

  • amyotrophic lateral sclerosis type 1, modeled by the breed's Degenerative myelopathy via SOD1, the same underlying biology.
Human equivalents via OMIA → Mondo / OMIM. Model-of, not identity. The named gene is the canine locus, not a claim that a pet has the human disease.
Documented in OMIA

Every condition recorded in the Bloodhound

Beyond the testable carriers above, OMIA's literature catalogue records 1 genetic conditions in the Bloodhound, 1 of which have a known human equivalent. This is the documented landscape across all Bloodhounds ever studied, not a prediction for any one dog.

Online Mendelian Inheritance in Animals (OMIA); Nicholas, Tammen & Sydney Informatics Hub, DOI 10.25910/2AMR-PV70
Documented in the breed's literature is not carrier status and not a forecast for an individual dog. Human equivalents are mapped via Mondo/OMIM. Carrier frequencies (above) are the separately-measured testable subset (Donner 2023).
The data behind this page

Where every number on this page came from.

This page draws on three primary data sources. Carrier frequencies for the Mendelian section come from Donner et al. 2023 (CC-BY-4.0). We grade these data at evidence Limited because the cohort is a direct-to-consumer ascertainment, which biases toward owners who chose to test their dogs. The panel also uses tag-SNP proxies for some variants rather than direct causal-variant assays. Limited is a study-design grade, not a quality grade: the Donner cohort is the largest open canine-genotype dataset in existence and we are grateful for it. We rate the confounding MEDIUM.

Population-genetic dimensions (heterozygosity, intra-breed PCA distance, nearest neighbors, trait-locus frequencies) come from CanVAS (Brundage 2026), harmonized through the Sniff Atlas. The exact release date and verification commit are pinned at the bottom of the page so a researcher can trace a number back to a specific snapshot. The disease-gene-variant graph comes from OMIA (Online Mendelian Inheritance in Animals; Nicholas, Tammen, and the Sydney Informatics Hub at the Sydney School of Veterinary Science, The University of Sydney; retrieved April 2026, DOI 10.25910/2AMR-PV70).

What this page does not yet have. Inheritance modes and per-disease penetrance evidence from Donner 2023 are in the structured data for every variant the panel covers. Mondo, OMIM, Ensembl, and HGNC cross-references live on the gene and disease pages this page links to, rather than being repeated here. What is still absent from this breed page is anything not in the cited panel, and each such gap carries its cause where it appears.

How to cite this page. The computed dimensions on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.

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We can already place this breed on the atlas. We hold genetic diversity for n=18 of this breed in the atlas. Our floor for showing a cited rate is n=20. That is 2 more of this breed in our atlas, not in a published study.

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References
  1. Donner J, Freyer J, Davison S, Anderson H, Blades M, Honkanen L, et al. (2023). Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogs. PLOS Genetics 19(2):e1010651. doi:10.1371/journal.pgen.1010651
  2. Brundage DM (2026). CanVAS: A Harmonized and Imputed Canine Variant Atlas. bioRxiv. doi:10.64898/2026.04.13.718238
  3. Nicholas, F.W., Tammen, I., & Sydney Informatics Hub. (2026). Online Mendelian Inheritance in Animals (OMIA) [dataset]. The University of Sydney. https://omia.org. doi:10.25910/2AMR-PV70 (retrieved April 2026).
Last updated
Sources: CanVAS (Brundage 2026) · Donner 2023 · OMIA